Eugenia supra-axillaris Essential Oil and Its Nanoemulsion: Chemical Characterization, In Vivo Anti-Inflammatory, Analgesic, and Antipyretic Activities

Figure 4

Effect of oral administration of ESA-EO (50–100 mg/kg) and ESA-EO-NE (50–100 mg/kg) on the mean of paw thickness (carrageenan-induced paw edema in rats) after 1, 2, 3, 4, and 24 h of the tested drug administration. Data are expressed as mean ± SE. Positive control (a), diclofenac (30 mg/kg) (b), celecoxib (50 mg/kg) (c), ESA-EO (50 mg/kg) (d), ESA-EO (100 mg/kg) (e), ESA-EO-NE (50 mg/kg) (f), and ESA-EO-NE (100 mg/kg) (g).