Eugenia supra-axillaris Essential Oil and Its Nanoemulsion: Chemical Characterization, In Vivo Anti-Inflammatory, Analgesic, and Antipyretic Activities

Figure 5

Effect of oral administration of ESA-EO and ESA-EO-NE on TNF-α (a), and PGE2 (b), as compared to the standard drug, diclofenac (30 mg/kg) and celecoxib (50 mg/kg). Data are expressed as mean ± SE where n = 6. Statistics were carried out by one-way ANOVA and confirmed by Tukey’s multiple comparison test. was assumed to denote statistical significance. ^aStatistically significant from the control negative group. ^bStatistically significant from the carrageenan group. ^cStatistically significant from the diclofenac group. ^dStatistically significant from the celecoxib group.

(a)

(b)