Dihydromyricetin Alleviates Nonalcoholic Fatty Liver Disease and Its Associated Metabolic Syndrome by Inhibiting Endoplasmic Reticulum Stress in LDLR^−/− Mice Fed with a High-Fat and High-Fructose Diet

Figure 1

Diet-induced hyperlipidemia was alleviated in the DHM-treated LDLR^−/− mice: (a, b) plasma total triglyceride and cholesterol levels before and during the DHM challenge and ND or HFD feeding, (c) plasma high-density lipoprotein cholesterol levels after eight weeks of the ND or HFD feeding, and (d) plasma low-density lipoprotein cholesterol levels after eight weeks of ND or HFD feeding, n = 8 per group; ^#compared with the normal control group (ND); &, compared with the control group (HFD); ^#/&, ^##/&&, and ^###.

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