Research Article

SLC2A9 Gene Polymorphism Is Associated with Elevated Serum Uric Acid Caused by Pyrazinamide

Table 2

Genetic equilibrium status of SLC2A9, SLC22A12, and ABCG2.

SNPAlleleHWEaMAFMAF (1000 g-CHBS)b

SLC2A9rs1014290A/G0.3670.364G0.385G
rs11722228C/T0.8430.301T0.298T
rs13129697T/G0.7340.427G0.466G

SLC22A12rs3825016C/T0.0340.234T0.243T
rs475688T/C0.1230.427C0.459T
rs7929627A/G0.2870.381G0.428G
rs893006C/A0.0340.234A0.243A

ABCG2rs2054576A/G1.0000.203G0.231G
rs2231142G/T0.6730.273T0.284T
rs2728109A/C0.4560.213A0.224A
rs3114018C/A0.2950.385A0.630A

MAF, minor allele frequency. a, value of the Hardy–Weinberg equilibrium test; b, MAF of 1000 Genomes Project (Han Chinese in Beijing, China). Although unbalanced in the overall sample, they were normally distributed in the low-risk and high-risk groups (both and ).