Practicality of <i>STAT3</i> Gene Polymorphisms and Sorafenib Trough Concentration as Biomarkers for Sorafenib-Induced Hand-Foot Skin Reaction in Hepatocellular Carcinoma

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center"><i>N</i> = 43</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Development of HFSR, <i>n</i> (%)</td><td class="align_center">30 (69.8)</td></tr><tr><td class="align_left">Development by day 29, <i>n</i></td><td class="align_center">29</td></tr><tr><td class="align_left" colspan="2">Most severe grade, <i>n</i> (%)</td></tr><tr><td class="align_left"> Grade 1</td><td class="align_center">11 (36.7)</td></tr><tr><td class="align_left"> Grade 2</td><td class="align_center">15 (50.0)</td></tr><tr><td class="align_left"> Grade 3</td><td class="align_center">4 (13.3)</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>HFSR, hand-foot skin reaction.<br/></div></td></tr></table>

Journal of Clinical Pharmacy and Therapeutics

tab2

Table 2

Table 2: Practicality of <i>STAT3</i> Gene Polymorphisms and Sorafenib Trough Concentration as Biomarkers for Sorafenib-Induced Hand-Foot Skin Reaction in Hepatocellular Carcinoma 

Table 2 | Practicality of STAT3 Gene Polymorphisms and Sorafenib Trough Concentration as Biomarkers for Sorafenib-Induced Hand-Foot Skin Reaction in Hepatocellular Carcinoma 