Practicality of STAT3 Gene Polymorphisms and Sorafenib Trough Concentration as Biomarkers for Sorafenib-Induced Hand-Foot Skin Reaction in Hepatocellular Carcinoma

Table 3

Relationship between the STAT3 rs4796793 polymorphism and HFSR up to day 29.

	HFSR onset			HFSR severity
	HFSR (−)	HFSR (+)		Grade ≤ 1	Grade ≥ 2
GG	2	4	0.65	4	2	0.50
GC, CC	12	25		21	16

HFSR, hand-foot skin reaction.