Efficacy of Sofosbuvir/Daclatasvir in a Single Tablet for Treating Chronic Viral Hepatitis C

Table 4

Clinical assessment and laboratory tests.

Laboratory tests	n	Day 0		n	Week 24		n	Week 36		value
		Median	IQR		Median	IQR		Median	IQR
Naïve noncirrhotic patients
ALT	68	36.50	25.53	26	15.00	12.50	2	20.65	.	1.000
WBCs	65	5800.00	6575.82	25	7500.00	2985.00	2	12290.00	.	0.223
Hemoglobin	67	13.50	2.40	25	13.50	2.50	2	12.50	.	0.607
Platelets	68	213500	248925	25	254000	134550	2	305000	.	1.000
Creatinine clearance	17	66.20	92.1415	6	9.38	3.11	1	—	—	0.368
Naïve cirrhotic patients
ALT	19	78.50	71.31	18	24.00	19.30	12	29.75	17.30	0.005
WBCs	19	5490.00	2560.00	18	5265.00	2285.00	12	6170.00	2343.00	0.076
Hemoglobin	19	13.40	3.30	18	13.20	2.10	12	14.00	1.80	0.920
Platelets	19	156000	98000	18	151500	95550	12	197000	107750	0.529
Creatinine clearance	13	10.01	84.21	8	11.53	85.22	7	10.15	4.25	0.022
Pretreated noncirrhotic patients
ALT	5	32.40	25.01	3	16.60	.	3	16.40	.	0.097
WBCs	5	7470.00	6255.00	3	9820.00	.	3	8400.00	.	0.717
Hemoglobin	5	16.30	2.55	3	15.30	.	3	14.60	.	0.097
Platelets	5	268000	139000	3	276000	.	3	285000	.	0.717
Creatinine clearance	—	—	—	—	—	—	—	—	—	—