Development and Internal Validation of Machine Learning Algorithms for Determining Sodium Valproate Concentrations below the Standard Level Using a Risk Prediction Model of Children with Epilepsy

Figure 5

Sodium valproate concentrations below the standard level of nomogram evaluation and clinical use in children with epilepsy. (a–d) Calibration plots (a), GiViTi calibration band (b), decision curve analysis (c), and clinical impact plot (d) for predicting sodium valproate concentrations below the standard level in the development group. (e–h) Calibration plots (e), GiViTi calibration band (f), decision curve analysis (g), and clinical impact plot (h) for predicting sodium valproate concentrations below the standard level in the validation group.

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