Tirofiban on Fully Recanalized Stroke with Thrombectomy: A Propensity Score Matching Analysis
Table 1
Baseline characteristics of patients before and after PSM.
Variables
Before PSM
After PSM
Nontirofiban (n = 118)
Tirofiban (n = 185)
value
Nontirofiban (n = 85)
Tirofiban (n = 85)
value
Demography
Age (y), mean (SD)
65.1 ± 13.7
63.2 ± 12.4
0.202
64.6 ± 13.1
64.4 ± 11.9
0.922
Male, n (%)
63 (53.4%)
134 (72.4%)
0.001
50 (58.8%)
53 (62.4%)
0.638
Vascular risk factors
Hypertension
77 (65.3%)
123 (66.5%)
0.825
57 (67.1%)
54 (63.5%)
0.629
Diabetes
27 (22.9%)
63 (34.1%)
0.038
24 (28.2%)
23 (27.1%)
0.864
Hyperlipidemia
62 (52.5%)
110 (59.5%)
0.236
47 (55.3%)
43 (50.6%)
0.539
Current smoking
34 (28.8%)
72 (38.9%)
0.072
29 (34.1%)
31 (36.5%)
0.748
Current drinking
27 (22.9%)
63 (34.1%)
0.038
23 (27.1%)
24 (28.2%)
0.864
Atrial fibrillation
64 (54.2%)
59 (31.9%)
<0.001
37 (43.5%)
38 (44.7%)
0.877
Previous stroke
28 (23.7%)
28 (15.1%)
0.060
21 (24.7%)
17 (20.0%)
0.461
Coronary heart disease
37 (31.4%)
35 (18.9%)
0.013
22 (25.9%)
20 (23.5%)
0.722
Drug use prestroke
Anticoagulation, n (%)
18 (15.3%)
13 (7.0%)
0.021
12 (14.1%)
12 (14.1%)
0.099
Antiplatelet, n (%)
42 (35.6%)
56 (30.3%)
0.334
27 (31.8%)
29 (34.1%)
0.744
Admission characteristics
SBP (mmHg), mean (SD)
141.2 ± 21.8
145.8 ± 23.4
0.089
144.1 ± 21.8
142.5 ± 23.0
0.674
DBP (mmHg), mean (SD)
81.0 ± 14.4
84.4 ± 13.7
0.040
82.5 ± 15.0
83.1 ± 14.2
0.822
NIHSS, median (IQR)
15 (7)
14 (7)
0.026
15 (7)
15 (6)
0.794
ASPECTS, median (IQR)
9 (3)
9 (2)
0.674
9 (3)
9 (2)
0.595
Vessel occlusion site
ICA occlusion
33 (28.0%)
83 (44.9%)
0.003
30 (35.3%)
30 (35.3%)
0.999
MCA occlusion
85 (72.0%)
102 (55.1%)
55 (64.7%)
55 (64.7%)
Stroke etiology
LAA
35 (29.7%)
110 (59.5%)
<0.001
34 (40.0%)
35 (41.2%)
0.799
CE
73 (61.8%)
66 (35.6%)
46 (54.1%)
43 (50.6%)
Others
10 (8.5%)
9 (4.9%)
5 (5.9%)
7 (8.2%)
Treatment information
IVT, n (%)
52 (44.1%)
72 (38.9%)
0.374
38 (44.7%)
30 (35.3%)
0.210
General anesthesia, n (%)
35 (29.7%)
42 (22.7%)
0.175
25 (29.4%)
18 (21.2%)
0.217
OTP (min), median (IQR)
329 (223)
394 (261)
0.003
365 (235)
394 (259)
0.385
OTR (min), median (IQR)
405 (203)
455 (246)
0.005
436 (227)
450 (268)
0.608
Additional intra-arterial thrombolysis, n (%)
1 (0.8%)
2 (1.1%)
0.999
0 (0%)
1 (1.2%)
0.999
SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; ASPECTS, Alberta stroke program early computed tomography score; ICA, internal carotid artery; MCA, middle cerebral artery; LAA, large artery atherosclerosis; CE, cardioembolism; IVT, intravenous thrombolysis; OTP, time interval from symptom onset to puncture; OTR, time interval from symptom onset to recanalization. The bold values mean P < 0.05.
