Investigation of the Potential Targets and Mechanism Actions of Berberine in the Treatment of Pulpitis Based on Bioinformatics Analysis

Table 2

GO-BP enrichment analysis (top 10).

ID	Description	value	Genes	Count
GO:0150077	Regulation of neuroinflammatory response	2.69E − 12	MMP9, TNF, IL-6, PTGS2, IL1B	5
GO:0032496	Response to lipopolysaccharide	4.04E − 12	CXCL8, TNF, IL-6, PTGS2, FOS, IL1B, EDN1	7
GO:0002237	Response to molecule of bacterial origin	6.33E − 12	CXCL8, TNF, IL-6, PTGS2, FOS, IL1B, EDN1	7
GO:0150076	Neuroinflammatory response	5.51E − 11	MMP9, TNF, IL-6, PTGS2, IL1B	5
GO:0048661	Positive regulation of smooth muscle cell proliferation	2.43E − 10	MMP9, TNF, IL-6, PTGS2, EDN1	5
GO:0002675	Positive regulation of acute inflammatory response	4.15E − 10	TNF, IL-6, PTGS2, IL1B	4
GO:0051384	Response to glucocorticoid	1.47E − 09	TNF, IL-6, PTGS2, FOS, EDN1	5
GO:0045429	Positive regulation of nitric oxide biosynthetic process	1.96E − 09	TNF, PTGS2, IL1B, EDN1	4
GO:1904407	Positive regulation of nitric oxide metabolic process	2.15E − 09	TNF, PTGS2, IL1B, EDN1	4
GO:0006953	Acute-phase response	2.35E − 09	TNF, IL-6, PTGS2, IL1B	4