Chimeric Antigen Receptor-T (CAR-T) Cells as “Living Drugs”: A Clinical Pharmacist Perspective

Figure 5

Provision of CAR-T cell therapy from a pharmacist’s perspective. The ATMP clinical pharmacist plays an important role in the multidisciplinary team for the safe and effective provision of CAR-T cell therapy. They have a variety of responsibilities, including development of SOPs and guidelines within their institution, the building of treatment plans within the patient electronic medical record (EMR), ensuring the availability of at least two doses of tocilizumab for immediate treatment of CRS, and quality tracking of CAR-T cell therapy quality metrics. Pharmacists help manage CAR-T cell-associated toxicities, provide supportive care, verify medication prescriptions, ensure the chain of identity of the product and correct time and temperature storage, assist in logistics, provide patient and staff education, and furnish patients with a treatment wallet card.