Effect of Voriconazole on Tacrolimus Blood Concentration in Renal Transplant Recipients after Voriconazole Discontinuation

Table 2

Baseline laboratory test results before and after VRC discontinuation.

Parameter	Co-VRC	Post-VRC	t/Z
ALB(g/L)^a	36.23 ± 5.12	37.88 ± 6.39	−1.310	0.197
TBIL(µmol/L)^b	9.70 (7.95, 13.40)	10.00 (8.10, 13.13)	−0.920	0.358
ALT (U/L)^b	20.00 (16.00, 32.25)	24.50 (17.00, 49.25)	−1.559	0.119
AST (U/L)^b	18.00 (14.00, 28.00)	20.50 (15.75, 44.25)	−0.961	0.337
CRE (µmol/L)^b	210 (130.05, 383.65)	180.75 (107.40, 329.35)	−1.797	0.072
CCR (mL/min)^b	32.50 (14.75, 57.25)	41.00 (19.00, 72.50)	−1.338	0.181
u-hsCRP (mg/L)^b	4.09 (1.93, 10.38)	4.19 (1.67, 28.77)	−0.845	0.398
HB (g/L)^a	88.65 ± 13.82	87.69 ± 15.14	0.371	0.713
HCV (%)^a	26.92 ± 4.17	26.87 ± 4.60	−0.053	0.958

Albumin (ALB), total bilirubin (TBIL), glutamic aminotransferase (ALT), glutamic oxalacetic aminotransferase (AST), CRE (blood creatinine), CCR (creatinine clearance), C-reactive protein (u-hsCRP), hemoglobin (HB), and erythrocyte specific volume (HCV). ^athe paired t-tes, mean ± SD; ^bthe Wilcoxon signed-rank test, median (IQR).