Cerebrospinal Pharmacokinetic Analysis and Pharmacodynamic Evaluation of Ceftriaxone in Pediatric Patients with Bacterial Meningitis

Figure 3

Visual predictive check plots representing observed serum (a) and CSF (b) concentrations normalized to 50 mg/kg of ceftriaxone the heavy and dotted line denote the median and 90% predicted intervals calculated from 1,000 simulations.

(a)

(b)