Cerebrospinal Pharmacokinetic Analysis and Pharmacodynamic Evaluation of Ceftriaxone in Pediatric Patients with Bacterial Meningitis

Figure 4

Probabilities of attaining pharmacokinetics (PK)/pharmacodynamics (PD) target (100% T > MIC) in cerebrospinal fluid (CSF) for ceftriaxone at specific MICs. The dotted lines represent 90% probability. Dosing regimens of 120 mg/kg/day are up to 4000 mg/day for pediatric patients over 33.3 kg.