Research Article
Effects of Triazole Antifungal Agents on the Plasma Concentration and Dosage of Cyclosporin in Patients with Aplastic Anaemia
Table 1
Patients’ demographic data and clinical characteristics.
| | Item | FCZ group (n = 18) | POS group (n = 7) | value |
| | Sex (male/female) | 11/7 | 1/6 | | | Age (years)a | 37.33 ± 11.93 | 38.78 ± 10.43 | 0.867 | | Height (cm)a | 166.06 ± 9.69 | 164 ± 5.15 | 0.306 | | Weight (kg)a | 63.19 ± 12.21 | 60.19 ± 10.88 | 0.443 | | Basic disease n (%) | | Hypertension | 1 (5.56) | 2 (28.57) | 0.180 | | Diabetes | 0 | 1 (14.29) | 0.280 | | RBC (1012/L) | 1.92 (1.72–3.07) | 1.81 (1.63–2.93) | 0.453 | | HGB (g/L) | 59.50 (55–97.75) | 68.5 (53.25–90.25) | 0.998 | | HCT (%) | 0.17 (0.15–0.27) | 0.19 (0.15–0.26) | 0.760 | | PLT (109/L) | 6 (3.75–20.25) | 12 (5.5–22.25) | 0.387 | | WBC (109/L) | 1.3 (0.80–2.87) | 1.56 (0.51–2.40) | 0.677 | | ALT (IU/L) | 15.45 (11.75–19.18) | 22.5 (11.63–170.03) | 0.278 | | AST (IU/L) | 13.35 (11.23–19) | 16.35 (14.3–62.80) | 0.133 | | TBIL (μmol/L) | 16.4 (10.78–28.03) | 18 (11.88–30.43) | 0.718 | | TP (g/L) | 63.1 (60.4–67.20) | 60.75 (55.4–64.28) | 0.130 | | ALB (g/L) | 36.6 (35.45–37.7) | 35.65 (30.9–37.08) | 0.210 | | Urea (mmol/L) | 5.80 (5.10–6.95) | 5.15 (3.9–7.2) | 0.382 | | Creatinine (μmol/L) | 60 (48.93–67) | 59.5 (47.5−2.75) | 0.520 |
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aData are mean ± SD. RBC, red blood cells; HGB, haemoglobin; HCT, haematocrit; PLT, blood platelets; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; TP, total protein; ALB albumin.
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