Phlorizin Prevents Glomerular Hyperfiltration but not Hypertrophy in Diabetic Rats

Table 2

Glomerular morphometry in Fischer rats at one-week diabetes: $n=$ number of rats, $N=$ total number of observations, GTV = glomerular tuft volume. Tuft $\text{A}=$ glomerular tuft area, MMA = mesangial matrix area. All variables were analyzed using one way ANOVA, and then between group differences were compared using unpaired two-tailed student's t-test.

	Control	Diabetic	DPLZ
	$n=5$, $N=72$	$n=6$, $N=89$	$n=5$, $N=70$
GTV	$486\pm 11$	$557\pm {11}^{***}$	$621\pm {153}^{***}$
$\mu {\text{m}}^3\times {10}^3$
Tuft A	$5293.9\pm 117.8$	$5796.7\pm {74.4}^{***}$	$6225.1\pm {102.9}^{***}$
$\mu {\text{m}}^2$
MMA	$163.3\pm 6$	$159.1\pm 4.5$	$164.6\pm 6.6$
$\mu {\text{m}}^2$
MMA/tuft A%	$3.07\pm 0.1$	$2.77\pm 0.1$	$2.65\pm {0.1}^{**}$

${}^{**}=P<.01$, ${}^{***}=P<.001$, compared to control.