Diabetes Alters Contraction-Induced Mitogen Activated Protein Kinase Activation in the Rat Soleus and Plantaris
Figure 4
Effects of concentric, maximal muscle contraction in situon phosphorylation of Jnk. The basal (control) and contraction-induced
phosphorylation of the Jnk1 (d),(e), Jnk2 (a),(b), Jnk3-MAPK (c) in plantaris
and soleus muscles from lean and diabetic Zucker rats
at 0, 1, and 3 hours after contractile stimulus. Jnk phosphorylation was
determined by Western analysis and immunodetection for Jnk phosphorylation on Thr183
and Tyr185. An asterisk (*) indicates significant difference ()
from the control within animal model, and a cross (†) indicates significant
difference ()
at corresponding time points across animal models.
