Dynamic Changes of Neuroskeletal Proteins in DRGs Underlie Impaired Axonal Maturation and Progressive Axonal Degeneration in Type 1 Diabetes
Figure 3
Levels of phosphorylated and total neurofilament subunits in DRGs. (a) total NFH; (b) total NFM; (c) total NFL; (d) SMI31 (phosphorylated NFM and NFH); and (e) Relative phosphorylation of NFM (ei) and NFH (eii) at 2-month, 7-month and 10-month of diabetes. Results are means SD (). *, ** and *** versus respective control rats. Expression of DRG tubulins. (f) betaIII-tubulin, (g) total beta-tubulin and (h) actin levels in DRGs at 2-month, 7-month and 10-month diabetic rats. Results are means SD () *, ** and *** versus respective control rats.
