Dynamic Changes of Neuroskeletal Proteins in DRGs Underlie Impaired Axonal Maturation and Progressive Axonal Degeneration in Type 1 Diabetes
Figure 6
Cdk5 (a) and p-GSK-3 (b) positive DRG neurons in 2-month and 10-month diabetic rats. Note frequent Cdk5 stainability of small DRG neurons at 2-month (a), which tended to decrease with duration of diabetes. The number of p-GSK-3 positive DRG neurons increased with duration of diabetes (b) and affected ganglion cells of all sizes. The bar in the lower Figure 5(b) equals 35 m and indicates the magnification of all frames.
