Altered Expression of Somatostatin Receptors in Pancreatic Islets from NOD Mice Cultured at Different Glucose Concentrations In Vitro and in Islets Transplanted to Diabetic NOD Mice In Vivo
Figure 3
Syngeneic pancreatic islets in groups of 200 islets were transplanted beneath the kidney capsule, and the animal was sacrificed on day 3 after transplantation. A representative graft in a transplanted diabetic NOD mouse stained for insulin (green, (a)–(e)) coexpressing sst1-5 (yellow, (f)–(j)). (k)–(o) show a representative graft in transplanted diabetic NOD mice single stained with sst1-5-specific antibodies. Bar = 50 μm.