Review Article
TGR5: A Novel Target for Weight Maintenance and Glucose Metabolism
Table 2
List of currently available synthetic TGR5 ligands.
| | A: semisynthetic steroidal ligands | | | 23(S)-methyl-CA | | | 23(S)-methyl-CDCA | | | 6alpha-ethyl-23(S)-methyl-3alpha, 7alpha-dihydroxy-5beta-cholan-24-oic acid | | | 6alpha-ethyl-23(S)-methyl-CA (INT777) | |
| | B: nonsteroidal ligands | | | Quinazolinones | | | Imidazol[1,2-a][]doazepin | | | Quinolines | | | BR27 | | | 3-aryl-4-isoxazolecarboxamides | | | 6-methyl-2-oxo-4-thyiophen-2-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid-benzeyl ester | |
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