Research Article

Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes

Figure 4

Treatment with DR suppresses the number of ED-1-positive cells in the kidney of WFRs. ((a)-(A) through (H)) Representative photomicrographs of renal ED-1-positive cells in the four groups of rats. Data are the results of independent experiments in each group with six mice per group. Original magnification, ×400 for glomerular ED-1 staining and ×100 for tubule-interstitial ED-1 staining. (b) and (c) ED-1-positive cells in glomerular and tubulointerstitial lesions. Data are means ± SD ( , # versus other groups, ## versus other groups).
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