Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes

Figure 6

Acetylated-NF-κB (p65) and Sirt1 expression in the kidney. (a) Representative immunoblots of Sirt1, acetylated-NF-κB (p65), and NF-κB in protein extracts from the kidneys of rats of each group. Actin was loaded as an internal control. (b) Quantitative analysis of acetylated-NF-κB (p65) protein expression. (c) Quantitative analysis of Sirt1 protein expression. Data are means ± SD (𝑛=6, ^#𝑃<0.01 versus other groups, ^##𝑃<0.05 versus other groups).

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