Clinical Study
HLA Class II Alleles Susceptibility Markers of Type 1 Diabetes Fail to Specify Phenotypes of Ketosis-Prone Diabetes in Adult Tunisian Patients
Table 1
Demographic and clinical characteristics of the 4 KPD subgroups.
| | A+β− | A+β+ | A−β+ | A−β− | P |
| | N (%) | 10 (23.3) | 5 (11.6) | 18 (41.8) | 10 (23.3) | — | | Age (years) | 36.3 ± 4.9 | 47 ± 3.8 | 46.6 ± 10.9 | 54 ± 1.4 | .005 | | Men-to-women ratio | 8/2 | 3/2 | 11/7 | 6/4 | ns | | Family history of type 1 diabetes (%) | 6 (60) | 5 (60) | 9 (50) | 6 (60) | ns | | BMI (Kg/m2) | 24.2 ± 5.2 | 29.8 ± 4.1 | 25.5 ± 5.2 | 25 ± 4 | ns | | C-peptide at baseline (ng/ml) | 0.39 ± 0.29 | 1.42 ± 0.45 | 1.68 ± 0.76 | 0.48 ± 0.27 | <.0001 | | C-peptide after stimulation(ng/ml) | 0.55 ± 0.31 | 2.07 ± 1.03 | 2.10 ± 1.04 | 0.71 ± 0.35 | <.0001 | | Insulin requirement at 6 months | 10 (100) | 4 (80) | 13 (72.1) | 10 (100) | ns |
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ns: non significant and BMI: body mass index.
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