Glibenclamide Induces Collagen IV Catabolism in High Glucose-Stimulated Mesangial Cells

Figure 5

Representative immunoblotting and zymography in samples obtained from rat mesangial cells after chronic exposure (8 weeks) to high glucose with and without treatment with glibenclamide. MMP2 are samples of whole cell lysates. MMP2 lysis are samples of 24-hour conditioned media. The location of standards for molecular size identification is noted.