Research Article

Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis

Table 1

NO production and eNOS activity in different groups (means ± SD). Data show reduced NO production and decreased eNOS activity in DN glomeruli, and propyl gallate restored eNOS activity and NO production.

control groupDN groupPG group

NO ( 𝜇 mol/L) 1 2 7 . 3 6 ± 4 5 . 8 5 5 5 . 8 1 ± 1 6 . 8 2 * 9 5 . 3 8 ± 2 2 . 1 6 #
eNOS activity (U/mL) 5 8 . 4 2 ± 1 1 . 1 7 2 5 . 7 4 ± 7 . 3 7 * 3 9 . 3 1 ± 8 . 4 9 #

*Significantly different compared to control group ( 𝑃 < 0 . 0 5 ). #Significantly different compared to DN group ( 𝑃 < 0 . 0 5 ).