Severe Maternal Hyperglycemia Exacerbates the Development of Insulin Resistance and Fatty Liver in the Offspring on High Fat Diet

Figure 2

Maternal STZ treatment during gestation alters perinatal outcomes. Birth weight (a), litter size (b), and survival rate of pups at 7-day-age (c) were monitored for the offspring from citrate buffer-treated control dams (CON, 𝑛=54) or streptozotocin-treated dams (STZ, 𝑛=71). Values are means ± SEM; statistically significant differences are indicated by ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared with CON.

(a)

(b)

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