Suppression of the Nuclear Factor Eny2 Increases Insulin Secretion in Poorly Functioning INS-1E Insulinoma Cells
Figure 1
RT-PCR detection of Eny2 mRNA expression in mouse pancreatic islets and INS-1E insulinoma cells: knockdown by two specific siRNAs. (a) The mRNA of Eny2 was detected in isolated mouse pancreatic islets (left panel) and in INS-1E insulinoma cells (right panel). (b) Eny2 mRNA is efficiently knocked down 72 hours after transfection of INS-1E cells with 2 specific siRNAs (numbers 1 and 3) but not with a scrambled control siRNA.
