Inhibition of Aldose Reductase Activates Hepatic Peroxisome Proliferator-Activated Receptor-α and Ameliorates Hepatosteatosis in Diabetic db/db Mice
Figure 1
Effect of zopol treatment or AR knock-down on serum TG levels (a) and TC levels (b) of db/db mice. Lean control mouse groups are db/m, and db/m + zopol, ; diabetic mouse groups are db/db, ; db/db + zopol, and db/db + pLV-shNC (); db/db + pLV-shAR (). Values are expressed as the mean ± SEM. *; NS: not significant.
