In Vivo Efficacy of HD0471953: A Novel GPR119 Agonist for the Treatment of Type 2 Diabetes Mellitus

Figure 1

Increase in cytoplasmic cAMP level by HD0471953 in the HIT-T15 cell line. Test media containing HD0471953 were added to the cells for 90 min. Intracellular cAMP levels were measured after drug treatment by homogeneous time-resolved fluorescence.