Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia

Figure 1

Effect of hypoxia and encapsulation on insulin secretion at 1.6 and 16.7 mM glucose. ^$𝑃<0.02 for the stimulatory effect of 16.7 mM glucose, *𝑃<0.02 for the effect of hypoxia, ^¤𝑃<0.04 for the effect of encapsulation, and ^#𝑃<0.02 for the effect of hypoxia on encapsulated versus nonencapsulated islets at basal secretion. Data are mean ± SEM of eight separate experiments (five-six parallels per experimental condition), one-three experiments per donor (four donors).