Ethyl Pyruvate Prevents Methyglyoxal-Induced Retinal Vascular Injury in Rats

Figure 1

Retinal vascular cell apoptosis in intravitreally MGO-injected rat eyes. The trypsin-digested retinal vessels from a saline-injected eye (a), a MGO-injected eye (b), and an EP-treated eye (c) were stained with TUNEL (green). (d) Quantitative analysis of the TUNEL-positive cells. The values in the bar graphs represent the means ± SE, 𝑛=8. ^∗𝑃<0.01 versus the control group, ^#𝑃<0.01 versus the MGO-injected group.

(a)

(b)

(c)

(d)