Therapeutic Potential of Dioscorea Extract (DA-9801) in Comparison with Alpha Lipoic Acid on the Peripheral Nerves in Experimental Diabetes

Figure 4

Immunohistochemistry of cutaneous small nerve fibers of the foot dorsum (a) and the IENF density (b) of the experimental groups. PGP 9.5-stained small nerve fibers are more preserved and less shortened, and IENF density was higher in the DM+DA-9801 group than its non-DA-9801-treated DM groups. Data are presented as means ± SD. ^∗𝑃<0.05 versus Normal and ^∗∗𝑃<0.05 versus DM (𝑁=10 in each group). ALA: Alpha lipoic acid and DM: diabetes. Bar indicates the 100 µm.

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