The Effect of Dantonic Pill on β-Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy
Figure 1
Effect of DP and irbesartan treatments on the renal pathological changes. (a) Renal pathological changes of mesangial expansion were examined by histological staining (HE and PAS), and thickness of the GBM was determined by electron microscopy, as described in the materials and methods section. (A)(E)(I) Normal renal cortex in the control group. (B)(F)(J) STZ + vehicle group. (C)(G)(K) STZ + DP (500 mg/(kg·day) group. (D)(H)(L) STZ + irbesartan (50 mg/(kg·day)) group. (b) Thickness of the GBM (A) and mesangial expansion index (B) expressed as a quantitative estimate score. All values are the means ± SD (). , compared with the STZ + vehicle group.
