Brain Aging and AD-Like Pathology in Streptozotocin-Induced Diabetic Rats
Figure 2
Changes in the brain sterostructure of STZ-induced diabetic rats. (a) Representative forebrain images at 4 months after STZ injection. (b) Forebrain volume measurement (see Materials and Methods for procedure details). (c) Representative images of rat hippocampus at 4 months after STZ injection. (d) Hippocampal volume measurement (see Materials and Methods for procedure details). , significant difference compared with the age-matched control rats; . ((e) and (f)) Total RNA and protein concentrations were measured in whole brain at 4 months after STZ injection. , significant difference compared with the age-matched control group; .
