Association of Pulse Pressure with Serum TNF-α and Neutrophil Count in the Elderly

Table 1

Anthropometric and biochemical characteristics of 150 free-living elderly women studied and correlation coefficients of brachial pulse pressure.

	Mean ± SD	Pulse pressure
		Simple	Partial
Age (years)	75.5±8.2	0.375***	Adjusted
BMI (kg/m^2)	22.4±2.8	−0.051	0.034
Body fat percentage (%)	32.8±6.8	0.078	0.149
Systolic blood pressure (mmHg)	143±19	0.841***	0.846***
Diastolic blood pressure (mmHg)	84±10	0.335***	0.367***
Pulse pressure (mmHg)	59±12	1.000	1.000
Plasma glucose (mg/dL)	86±9	0.057	0.062
Insulin (𝜇U/mL)	5.4±4.0	−0.017	−0.003
log insulin	0.66±0.23	−0.017	0.026
HOMA-IR	1.18±0.97	−0.001	−0.011
log HOMA-IR	−0.012±0.25	−0.001	0.036
Total cholesterol (mg/dL)	221±30	−0.059	−0.003
HDL-cholesterol (mg/dL)	67±15	−0.136	−0.175*
LDL-cholesterol (mg/dL)	130±28	0.029	0.103
Triglyceride (mg/dL)	118±65	0.026	−0.015
Serum uric acid (mg/dL)	4.7±1.0	0.022	0.078
Serum creatinine (mg/dL)	0.72±0.15	0.141	0.027
Cystatin C (mg/L)	0.84±0.19	0.312***	0.133
eGFR (mL/min/1.73 m^2)	62±13	−0.184*	−0.014
Leptin (ng/mL)	8.8±5.8	0.026	0.112
Adiponectin (𝜇g/mL)	16.2±7.4	−0.003	−0.193*
hsCRP (𝜇g/dL)	211±355	0.266**	0.198*
Log hsCRP	1.88±0.60	0.266**	0.239**
TNF-𝛼 (pg/mL)	2.25±1.05	0.279***	0.274**
Log TNF-𝛼	0.30±0.21	0.279***	0.258**
PAI-1 (ng/mL)	28.3±10.5	0.069	0.256**
IL-6 (pg/mL)	4.69±5.95	0.211*	0.111
Log IL-6	0.47±0.39	0.211*	0.154
Neutrophils (×10^3/𝜇L)	3.27±1.09	0.165*	0.289***
Lymphocytes (×10^3/𝜇L)	2.03±0.59	0.065	0.109
Monocytes (×10^3/𝜇L)	0.31±0.10	0.252**	0.244**
Leukocytes (×10^3/𝜇L)	5.79±1.39	0.188*	0.293***
Hemoglobin (g/dL)	12.9±1.1	−0.120	−0.011

BMI: body mass index, HOMA-IR: homeostasis model assessment of insulin resistance, eGFR: estimated glomerular filtration rate, hsCRP: high-sensitivity C-reactive protein, TNF-𝛼: tumor necrosis factor-α, PAI-1: plasminogen activator inhibitor-1, and IL-6: interleukin-6. ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001.