Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1

Table 1

Serum proteins identified in diabetes mellitus.

Serial number	Category of protein	Name of protein	Expression in diabetics
1	Cytokines and cytokine-related proteins	Leptin	+
		TNF-alpha	+
		IL-6	+
2	Other immune-related proteins	MCP-1	+
3	Proteins involved in fibrinolytic system	PAI-1	+
		Tissue factor	+
4	Complement and complement-related proteins	Adipsin (complement factor D)	+
		ASP	+
		Adiponectin	−
5	Lipids and proteins for lipid metabolism or transport	Lipoprotein lipase (LPL)	+
		Apolipoprotein E	+
		Apolipoprotein A1,	−
		Apolipoprotein A2	−
		Apolipoprotein B	+
		Apolipoprotein H	−
		Apolipoprotein C1, C2	−
		NEFAs	+
		Cholesterol ester transferase protein (CETP)	+
6	Inflammatory proteins	C-reactive protein (CRP)	+
		α-tumor necrosis factor (αTNF)	+