Alloxan-Induced Diabetes Causes Morphological and Ultrastructural Changes in Rat Liver that Resemble the Natural History of Chronic Fatty Liver Disease in Humans
Table 2
Medians, maximum, and minimum values of parameters related to lipids profile of nondiabetic control and untreated diabetic rats during the various experimental follow-up periods.
Groups
Follow-up
Parameters
Total cholesterol
HDL cholesterol
LDL cholesterol
Triglycerides
(mg/dL)
(mg/dL)
(mg/dL)
(mg/dL)
NC
2 weeks
176.0 (152–206)
48.0 (45–58)
22.0 (15–28)
118.0 (98–135)
UD
180.5 (160–210)
46.0 (40–48)
25.0 (18–32)
125.0 (106–146)
value
0.3864
0.6236
0.3240
0.4412
NC
6 weeks
186.5 (178–202)
54.5 (45–60)
17.5 (13–26)
122.5 (104–132)
UD
188.5 (180–197)
50.5 (47–60)
18.5 (16–26)
127.0 (110–140)
value
0.6842
0.7394
0.4359
0.4813
NC
14 weeks
189.0 (186–200)
55.5 (48–60)
18.0 (16–20)
121.0 (119–140)
UD
192.5 (182–204)
53.0 (49–58)
20.0 (18–24)
127.5 (118–132)
value
0.8857
0.6857
0.2000
0.8857
NC
26 weeks
191.0 (188–195)
52.5 (46–60)
18.5 (16–22)
133.0 (125–142)
UD
199.0 (186–215)
47.0 (42–50)
23.0 (19–24)
135.0 (122–152)
value
0.3429
0.2000
0.1143
0.8857
NC: nondiabetic control; UD: untreated diabetic. NC = UD at 2, 6, 14, and 26 weeks of follow-up (Mann-Whitney test).
