Research Article

Alloxan-Induced Diabetes Causes Morphological and Ultrastructural Changes in Rat Liver that Resemble the Natural History of Chronic Fatty Liver Disease in Humans

Table 3

Mean ± SD of fresh liver weight (g) and fresh liver weight/body weight ratio of nondiabetic control rats and untreated diabetic rats during the various experimental follow-up periods.

GroupsParameters and follow-up
Fresh liver weight (g)Fresh liver weight/body weight ratio
6 weeks14 weeks26 weeks6 weeks14 weeks26 weeks

NC11.1420 ± 1.605012.3300 ± 1.008012.3320 ± 2.17000.0445 ± 0.00360.0277 ± 0.00410.0243 ± 0.0034
UD10.8990 ± 1.04309.5560 ± 1.043011.5040 ± 0.57720.0463 ± 0.00410.0555* ± 0.01280.0595* ± 0.0104

value0.10760.08650.30750.3064<0.0001<0.0001

NC: nondiabetic control; UD: untreated diabetic.
*NC < UD at 14 and 26 weeks of follow-up (Student’s -test).