Protective Effects of the Mushroom Lactarius deterrimus Extract on Systemic Oxidative Stress and Pancreatic Islets in Streptozotocin-Induced Diabetic Rats

Figure 3

The effect of administration of the L. deterrimus extract on histological changes and immunohistochemical localization of insulin and CXCL12 in pancreatic islets. HE: hematoxylin and eosin staining of pancreatic sections; light photomicrographs of insulin, CXCL12, and CXCR4 immunohistochemical staining of pancreatic sections within islets (magnification 40x). NDM: control rats; NDM + Ld: control rats treated daily with L. deterrimus extract for four weeks; DM: STZ-induced diabetic rats; DM + Ld: STZ-induced diabetic rats treated with L. deterrimus extract for four weeks.