Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts

Figure 4

Effect of low glucose (LG) and glucose (G) on cardiac 15-F2t-isoprostane (15-F2t-IsoP) and cardiac CD36 protein expression. Cardiac 15-F2t-IsoP, a specific index of ROS-induced oxidative stress, was higher in LG that was associated with higher cardiac lipid transporter CD36 protein expression than in G. Propofol significantly reduced 15-F2t-IsoP as well as CD36 in G but not in LG. TMZ did not change the protein level of CD36 in LG. BS20 is abbreviation of 20 min after stabilization. Values are presented as mean ± SEM. per group. versus BS20; versus LG; versus LG+P.

(a)

(b)