ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes

Figure 3

Disulfiram (DSF) pretreatment and 4HNE protein adducts. (a) Western blot images of 4HNE adducts were shown. Beta-actin was used as a loading control. (b) The quantification data of Western immunoblot. Disulfiram (DSF) (10 μM) treatment increases 4HNE protein adduct formation; the data expressed are mean ± SEM. = 4–6. G1, G2, G3, and G4 depict mannitol, high glucose stress, DSF + mannitol, and DSF + high glucose stress, respectively. versus G1, versus G2, and versus G3.

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