Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6

Figure 2

The oral glucose tolerance and insulin resistance test in Mig-6^f/f and Mig-6^d/d mice. (a) Oral glucose tolerance (left panel) and AUC of plasma plasma glucose concentration during the OGTT (right panel) at 23 weeks of age. (b) Change in plasma glucose concentration during insulin tolerance test (left panel), AUC of plasma plasma glucose concentration during the ITT (middle panel), and (right panel) at 23 weeks of age. , , and indicate , , and , versus LFD treated group in the same genotype, respectively. , , and indicate , , and , versus Mig-6^f/f, respectively. Data are presented as mean ± SE from 9 to 10 mice per group.

(a)

(b)