Research Article

Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity

Table 1

Demographic and laboratory features of patients with patients and controls.

DFU patients ()Control group () value

Age (years)62.0 ± 10.30.054
Gender (F/M)57 (37.5%)/95 (62.5%)19 (36.5%)/33 (63.5%)0.902
Duration of diabetes (years)12.8 (11.6, 14.1)11.3 (8.8, 13.7)0.249
Smoking (%)37.40%38.90%0.781
Drinking (%)35.00%30.60%0.7
BMI (kg/m2)25.09 (24.28, 25.90)25.21 (22.17, 28.25)0.941
SBP (mmHg)145.5 ± 22.7140.8 ± 18.60.262
DBP (mmHg)79.0 ± 15.883.7 ± 10.80.099
FBG (mmol/L)7.6 (7.1, 8.1)8.2 (7.2, 9.3)0.277
HbA1c (%)8.56 (8.18, 8.94)8.54 (7.13, 9.95)0.975
Hemoglobin (g/L)123.4 ± 21.7139.2 ± 18.3<0.0001
WBC (×109/L)8.3 ± 3.86.7 ± 1.8<0.0001
Neutrophil (×109/L)6.00 ± 3.613.79 ± 1.27<0.0001
Platelet (×109/L)255.8 ± 79.5233.5 ± 62.10.127
Fibrinogen (g/L)4.50 ± 1.493.01 ± 1.07<0.0001

Data were means ± SD or medians (interquartile range) or proportions for categorical variables. DFU: diabetic foot ulcer; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; FBG: fasting plasma glucose; HbA1c: glycosylated hemoglobin; WBC: white blood cell.