Carotid Intima-Media Thickness and Visit-to-Visit HbA1c Variability Predict Progression of Chronic Kidney Disease in Type 2 Diabetic Patients with Preserved Kidney Function
Table 2
Baseline clinical and biochemical characteristics of 162 type 2 diabetic patients whose kidney function deteriorated and did not deteriorate over a 6.0-year follow-up.
Deterioration
values
Present ()
Absent ()
Male sex (, %)
21, 53
68, 56
0.72
Smokers (, %)
14, 35
39, 32
0.75
Age (years)
0.01
BMI (kg/m2)
0.52
Waist circumference (cm)
0.52
Duration of diabetes (years)
0.35
Treatment of diabetes; diet/OHA/insulin (, %)
12/21/7, 30/53/18
41/60/21, 34/49/17
0.91
Hypertension; CCB/RASi/diuretics (, %)
17/16/3, 43/40/8
39/52/4, 32/43/3
0.41
HbA1c (%)
0.42
Fasting PG (mg/dL)
0.97
Postbreakfast PG (mg/dL)
0.87
CV-HbA1c (%)
0.15
Total cholesterol (mg/dL)
0.998
LDL cholesterol (mg/dL)
0.92
HDL cholesterol (mg/dL)
0.28
Fasting TG (mg/dL)
0.06
Postbreakfast TG (mg/dL)
0.17
Serum creatinine (mg/dL)
0.07
eGFR (mL/min/1.73 m2)
0.004
eGFR (mL/min/1.73 m2/year)
0.000
Uric acid (mg/dL)
0.048
Systolic BP (mmHg)
0.17
CV-systolic BP (%)
0.82
Diastolic BP (mmHg)
0.85
Urinary ACR (mg/g)
0.002
log ACR
0.013
Leucocyte count (103/μL)
0.046
Maximum IMT (mm)
0.03
Mean IMT (mm)
0.02
ACR ≥ 30 mg/g (, %)
17, 43
36, 30
0.13
Mean ± SD or , %. Abbreviations are the same as in Table 1.
