Research Article

Effects of the New Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m on High Glucose Induced Prolongation of Cardiac QT Interval and Increase of Coronary Perfusion Pressure

Figure 1

Representative pictures from hematoxylin and eosin staining of cardiac tissue. Rat hearts were perfused with Krebs solution containing (a) D-glucose 11.1 mM (control); (b) glucose 33.3 mM (high glu); (c) high glu + BF-5m (0.1 μM); (d) high glu + BF-5m (0.1 μM) + EX527 (10 mg/kg/day i.p.). 200x magnification; scale bar = 100 μm.
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