High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

Figure 7

Compared with the LPS (10 μg/L) group, mRNA and protein levels of TXNIP, NLRP3, procaspase-1, and IL-1β were significantly lower in the LPS (10 μg/L) plus NAC group (a, b) (NC: 0 μg/L LPS; LPS3: 10 μg/L LPS; NAC + LPS3: 10 μmol/L NAC + 10 μg/L LPS) (, versus NC group, versus LPS3 group).

(a)

(b)