The IL-1β Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice

Figure 6

Stereological analyses of nondiabetic and diabetic NOD mice pancreata. (a) β-cell mass, (b) β-cell mass versus BG, (c) non-β-cell mass, (d) unstained endocrine cell mass, and (e) immune cell mass in diabetic and nondiabetic vehicle and SER140 treated NOD mice. (f) β-cell mass versus immune cell mass. ((a), (c), (d), and (e)) Data are presented as mean ± SEM ( = 18-19/group); one-way ANOVA with Turkey’s multiple comparison test; versus vehicle normoglycemic mice.

(a)

(b)

(c)

(d)

(e)

(f)