Uninephrectomized High-Fat-Fed Nicotinamide-Streptozotocin-Induced Diabetic Rats: A Model for the Investigation of Diabetic Nephropathy in Type 2 Diabetes

Figure 6

Routine renal function markers in the control, NA-STZ, and LD-STZ groups during the experiment. (a) Dynamics of urinary albumin excretion (μg/24 h) measured at weeks 10, 20, and 30 of the experiment in the studied groups. (b) Dynamics of calculated clearance of creatinine (mL/min/kg) measured at weeks 10, 20, and 30 of the experiment in the studied groups. Mean values and standard deviations are shown. ○ – , ○○ – in NA-STZ diabetic group versus control nondiabetic group at the same point of measurement. ● – , ●● – in LD-STZ diabetic group versus control nondiabetic group at the same point of measurement. ■- in NA-STZ group versus LD-STZ group at the same point of measurement. compared to the first measurement in the same group at week 10.

(a)

(b)