Plasma C1q/TNF-Related Protein-3 (CTRP-3) and High-Mobility Group Box-1 (HMGB-1) Concentrations in Subjects with Prediabetes and Type 2 Diabetes

Table 4

Multiple logistic regression analyses of plasma HMGB-1 levels among various groups.

	Pre-DM		nT2DM
	OR, 95% CI	value	OR, 95% CI	value
Age, sex	5.436 (2.492, 11.858)	<0.001	14.436 (6.899, 26.796)	<0.001
+ALT, AST, GGT, Cr	5.142 (2.286, 11.564)	<0.001	9.81 (3.509, 15.284)	<0.001
SBP, DBP	5.173 (2.288, 11.696)	<0.001	10.798 (4.641, 21.068)	<0.001
TC, TG, LDL-C, HDL-C	5.505 (2.183, 13.879)	<0.001	7.805 (2.163, 17.853)	<0.001
WHR, BMI	5.115 (1.993, 13.125)	<0.001	3.754 (1.204, 9.281)	<0.001

Pre-DM, prediabetes states (including IFG, impaired fasting glucose; IGT, impaired glucose tolerance; IGR, impaired glucose regulation); T2DM, type 2 diabetes mellitus; OR, odds ratio; CI, confidence interval; ALT, alanine transaminase; AST, aspartate transaminase; γ-GGT, gamma-glutamyl transpeptidase; Cr, creatinine; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; WHR, waist-to-hip ratio; BMI, body mass index.